@article{5fe44cf9484247ca8e4f3b610f3369d9,
title = "YKT6 as a second SNARE protein of mammalian autophagosomes",
abstract = "Mammalian autophagosomes possess the Qa-SNARE STX17 (syntaxin 17) for fusion with lysosomes. However, STX17 is not absolutely required for fusion because STX17 knockout cells partially retain autophagosome-lysosome fusion activity. We recently identified YKT6, an R-SNARE, as another autophagosomal SNARE protein that acts independently of STX17 in mammals. Here, we discuss the features and functions of autophagosomal SNARE proteins by comparing STX17 and YKT6. Abbreviations: SNARE, soluble N-ethylmaleimide-sensitive factor attachment protein receptor; STX17, syntaxin 17.",
keywords = "Autophagosome, SNARE, YKT6, lysosome, syntaxin 17",
author = "Noboru Mizushima and Takahide Matsui and Hayashi Yamamoto",
note = "Funding Information: This work was supported by Grant-in-Aid for Scientific Research on Innovative Areas (Grant Number 25111005) from Japan Society for the Promotion of Science (JSPS) and Exploratory Research for Advanced Technology (ERATO) (Grant Number JPMJER1702) from Japan Science and Technology Agency (JST) to N.M. Publisher Copyright: {\textcopyright} 2018, {\textcopyright} 2018 Informa UK Limited, trading as Taylor & Francis Group.",
year = "2019",
month = jan,
day = "2",
doi = "10.1080/15548627.2018.1532262",
language = "English",
volume = "15",
pages = "176--177",
journal = "Autophagy",
issn = "1554-8627",
publisher = "Landes Bioscience",
number = "1",
}