抄録
It is important to understand the distribution of steroidogenesis in steroid producing tissues in order to obtain a better understanding of steroid metabolism. Recent advances in purification and subsequent generation of antibodies against cytochromes P-450 specificif or steroid hormone biosynthesis have made it possible to localize the sites of steroidogenesis immunohistochemically. This review provides the localization of sex-steroid hormone biosynthesis in normal and pathological human ovaries including sex-cord stromal tumors, hyperthecosis and Brenner tumor, as determined by the tissue distribution of immunoreactivity ofindividual enzymes specific for different stages of the biosynthetic process.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 942-948 |
| ページ数 | 7 |
| ジャーナル | Pathology Research and Practice |
| 巻 | 185 |
| 号 | 6 |
| DOI | |
| 出版ステータス | Published - 1989 1 1 |
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Cell Biology