What's New in the Localization of Sex Steroids in the Human Ovary and its Tumors?

H. Sasano, N. Sasano

研究成果: Article査読

9 被引用数 (Scopus)

抄録

It is important to understand the distribution of steroidogenesis in steroid producing tissues in order to obtain a better understanding of steroid metabolism. Recent advances in purification and subsequent generation of antibodies against cytochromes P-450 specificif or steroid hormone biosynthesis have made it possible to localize the sites of steroidogenesis immunohistochemically. This review provides the localization of sex-steroid hormone biosynthesis in normal and pathological human ovaries including sex-cord stromal tumors, hyperthecosis and Brenner tumor, as determined by the tissue distribution of immunoreactivity ofindividual enzymes specific for different stages of the biosynthetic process.

本文言語English
ページ(範囲)942-948
ページ数7
ジャーナルPathology Research and Practice
185
6
DOI
出版ステータスPublished - 1989 1 1

ASJC Scopus subject areas

  • 病理学および法医学
  • 細胞生物学

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