Usefulness of asialoglycoprotein receptor imaging for the evaluation of liver metastasis of neuroblastoma

Tomohiro Kaneta, Takashi Hakamatsuka, Hiroshi Ito, Shin Maruoka, Hiroshi Fukuda, Shoki Takahashi, Shogo Yamada

研究成果: Article

2 引用 (Scopus)

抜粋

Neuroblastoma, derived from the neural crest ectoderm, is the most common type of solid abdominal mass seen in infancy. The diagnosis, staging, and follow-up of neuroblastoma are often performed using metaiodobenzylguanidine (MIBG) imaging. However, the evaluation of liver metastasis by this method is complicated by the normal physiological uptake of MIBG by the liver. The asialoglycoprotein receptor is a hepatic cell-surface receptor specific for galactose-terminated glycoprotein, and 99mTc-DTPA-galactosyl human serum albumin (GSA) accumulates selectively in hepatic cells. Here, we report a case of congenital neuroblastoma with liver metastasis in which GSA scans were useful for differentiation between normal and metastatic sites in the liver.

元の言語English
ページ(範囲)355-358
ページ数4
ジャーナルAnnals of Nuclear Medicine
18
発行部数4
DOI
出版物ステータスPublished - 2004 6

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Kaneta, T., Hakamatsuka, T., Ito, H., Maruoka, S., Fukuda, H., Takahashi, S., & Yamada, S. (2004). Usefulness of asialoglycoprotein receptor imaging for the evaluation of liver metastasis of neuroblastoma. Annals of Nuclear Medicine, 18(4), 355-358. https://doi.org/10.1007/BF02984476