Use of sugammadex in patients for caesarean section undergoing general anesthesia with rocuronium

Masakazu Shibusawa, Yutaka Ejima, Ryou Nishino, Hiroaki Toyama, Shin Kurosawa

研究成果: Article査読

5 被引用数 (Scopus)

抄録

Recently, rocuronium is being used in patients for caesarean section undergoing general anesthesia instead of suxamethonium. An increased dose of rocuronium improves intubating conditions but prolongs neuromuscular blockade. Sugammadex reverses rapidly and predictably even profound rocuronium-induced neuromuscular blockade. We experienced 13 cases of caesarean section patients undergoing general anesthesia with thiopental (3.5 mg·kg -1) and rocuronium (0.9 mg·kg -1). At the end of surgery, sugammadex (2 mg·kg -1) was administered every 3 minutes repeatedly until TOF>0.9. In two patients, neuromuscular blockade spontaneously recovered to TOF>0.9 at the end of surgery. In most patients administered sugammadex, TOF recovered to more than 0.9 within a few minutes. However, in one patient who had chronic renal failure (creatinine clearance rate : 12 ml·min -1), 10 minutes were required for TOF to recover to more than 0.7, and TOF never reached 0.9. All patients were successfully intubated at the first attempt. No signs of recurarization or adverse effects related to sugammadex were noted in the perioperative period.

本文言語English
ページ(範囲)805-809
ページ数5
ジャーナルJapanese Journal of Anesthesiology
61
8
出版ステータスPublished - 2012 8 1

ASJC Scopus subject areas

  • 麻酔学および疼痛医療

フィンガープリント

「Use of sugammadex in patients for caesarean section undergoing general anesthesia with rocuronium」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル