抄録
In combination with an electrode modified with an abasic site-containing DNA duplex, flavins selectively bind to thymine with a useful electrochemical response, and flavins could be successfully utilized for detection of thymine-related mutations. The abasic site provides hydrophobic microenvironments for the hydrogen bond-forming ligands can recognize the specific target base in the DNA duplex, which is detected by the difference in the electrochemical response.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 91-92 |
| ページ数 | 2 |
| ジャーナル | Nucleic acids symposium series (2004) |
| 号 | 50 |
| DOI | |
| 出版ステータス | Published - 2006 |
ASJC Scopus subject areas
- 医学（全般）