Urinary polyamine evaluation for effective diagnosis of various cancers

Ja Won Suh, Seon Hwa Lee, Bong Chul Chung, Jongsei Park

研究成果: Article査読

46 被引用数 (Scopus)

抄録

With a newly modified analytical method, the concentrations of free and acetylated urinary polyamines were simultaneously determined in a control group (32 cases) and patients with various types of cancers (104 cases, 20 males and 84 females) by gas chromatography-nitrogen-phosphorus detection. Significant concentration differences between normal subjects and various cancer patients were found. The various types of cancers (advanced gastric carcinoma, ovarian cancer, acute myelocyte leukemia, non-Hodgkin's lymphoma) gave unique patterns of urinary polyamine profile as well as significant differences of concentration. To indirectly evaluate the possible involvement of enzymes, precursor-to-product concentration ratios were compared between controls and patients with various types of cancers.

本文言語English
ページ(範囲)179-186
ページ数8
ジャーナルJournal of Chromatography B: Biomedical Applications
688
2
DOI
出版ステータスPublished - 1997 1 24
外部発表はい

ASJC Scopus subject areas

  • 化学 (全般)

フィンガープリント

「Urinary polyamine evaluation for effective diagnosis of various cancers」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル