Ultrasound imaging of propagation of myocardial contraction for non-invasive identification of myocardial ischemia

Yuya Matsuno, Hirofumi Taki, Hiroaki Yamamoto, Michinori Hirano, Susumu Morosawa, Hiroaki Shimokawa, Hiroshi Kanai

研究成果: Article

12 引用 (Scopus)

抜粋

Non-invasive identification of ischemic regions is important for diagnosis and treatment of myocardial infarction. In the present study, ultrasound measurement was applied to the interventricular septum of three open-chest swine hearts. The properties of the myocardial contraction response of the septum were compared between normal and acute ischemic conditions, where the acute ischemic condition of the septum originated from direct avascularization of the left anterior descending (LAD) coronary artery. The result showed that the contraction response propagated from the basal side to the apical side along the septum. The estimated propagation velocities in the normal and acute ischemic conditions were 3.6 and 1.9m/s, respectively. This finding indicates that acute ischemia which occurred 5 s after the avascularization of the LAD promptly suppressed the propagation velocity through the ventricular septum to about half the normal velocity. It was suggested that the myocardial ischemic region could be identified using the difference in the propagation velocity of the myocardial response to contraction.

元の言語English
記事番号07JF05
ジャーナルJapanese journal of applied physics
56
発行部数7
DOI
出版物ステータスPublished - 2017 7

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

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