Trends of genetic relationship of serotype 23F penicillin-resistant streptococcus pneumoniae in Japan

Ryoji Yoshida; Yoichi Hirakata; Mitsuo Kaku; Hiromu Takemura; Hironori Tanaka; Kazunori Tomono; Hironobu Koga; Shigeru Kohno; Shimeru Kamihira

doi:10.1159/000239572

Trends of genetic relationship of serotype 23F penicillin-resistant streptococcus pneumoniae in Japan

Ryoji Yoshida, Yoichi Hirakata, Mitsuo Kaku, Hiromu Takemura, Hironori Tanaka, Kazunori Tomono, Hironobu Koga, Shigeru Kohno, Shimeru Kamihira

研究成果: Article › 査読

8 被引用数 (Scopus)

抄録

No data on the genetic analysis of penicillin-resistant Streptococcus pneumoniae (PRP) in Japan has been reported. The Smal restriction endonuclease digested patterns of chromosomal DNAs from 15 PRP serotyped 23F isolated in Japan were analyzed by pulsed-field gel electrophoresis (PFGE). The isolates were genetically heterogeneous and seven different PFGE patterns were identified. Nine strains were also resistant to erythromycin and tetracycline. Four strains revealed resistance to ceftriaxone. The PFGE patterns of some strains isolated in Nagasaki University Hospital were identical to each other and closely resembled those of isolates from three different areas of Japan. These results indicate a need for additional studies by PFGE to determine the possibility of clonal spread in Japan.

本文言語	English
ページ（範囲）	232-238
ページ数	7
ジャーナル	Chemotherapy
巻	43
号	4
DOI	https://doi.org/10.1159/000239572
出版ステータス	Published - 1997 1月 1
外部発表	はい

ASJC Scopus subject areas

腫瘍学
薬理学
創薬
薬理学（医学）
感染症

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

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10.1159/000239572

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title = "Trends of genetic relationship of serotype 23F penicillin-resistant streptococcus pneumoniae in Japan",

abstract = "No data on the genetic analysis of penicillin-resistant Streptococcus pneumoniae (PRP) in Japan has been reported. The Smal restriction endonuclease digested patterns of chromosomal DNAs from 15 PRP serotyped 23F isolated in Japan were analyzed by pulsed-field gel electrophoresis (PFGE). The isolates were genetically heterogeneous and seven different PFGE patterns were identified. Nine strains were also resistant to erythromycin and tetracycline. Four strains revealed resistance to ceftriaxone. The PFGE patterns of some strains isolated in Nagasaki University Hospital were identical to each other and closely resembled those of isolates from three different areas of Japan. These results indicate a need for additional studies by PFGE to determine the possibility of clonal spread in Japan.",

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author = "Ryoji Yoshida and Yoichi Hirakata and Mitsuo Kaku and Hiromu Takemura and Hironori Tanaka and Kazunori Tomono and Hironobu Koga and Shigeru Kohno and Shimeru Kamihira",

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AU - Yoshida, Ryoji

AU - Hirakata, Yoichi

AU - Kaku, Mitsuo

AU - Takemura, Hiromu

AU - Tanaka, Hironori

AU - Tomono, Kazunori

AU - Koga, Hironobu

AU - Kohno, Shigeru

AU - Kamihira, Shimeru

PY - 1997/1/1

Y1 - 1997/1/1

N2 - No data on the genetic analysis of penicillin-resistant Streptococcus pneumoniae (PRP) in Japan has been reported. The Smal restriction endonuclease digested patterns of chromosomal DNAs from 15 PRP serotyped 23F isolated in Japan were analyzed by pulsed-field gel electrophoresis (PFGE). The isolates were genetically heterogeneous and seven different PFGE patterns were identified. Nine strains were also resistant to erythromycin and tetracycline. Four strains revealed resistance to ceftriaxone. The PFGE patterns of some strains isolated in Nagasaki University Hospital were identical to each other and closely resembled those of isolates from three different areas of Japan. These results indicate a need for additional studies by PFGE to determine the possibility of clonal spread in Japan.

AB - No data on the genetic analysis of penicillin-resistant Streptococcus pneumoniae (PRP) in Japan has been reported. The Smal restriction endonuclease digested patterns of chromosomal DNAs from 15 PRP serotyped 23F isolated in Japan were analyzed by pulsed-field gel electrophoresis (PFGE). The isolates were genetically heterogeneous and seven different PFGE patterns were identified. Nine strains were also resistant to erythromycin and tetracycline. Four strains revealed resistance to ceftriaxone. The PFGE patterns of some strains isolated in Nagasaki University Hospital were identical to each other and closely resembled those of isolates from three different areas of Japan. These results indicate a need for additional studies by PFGE to determine the possibility of clonal spread in Japan.

KW - Ceftriaxone resistant

KW - Erythromycin resistant

KW - Penicillin-resistant

KW - Pulsed-field gel electrophoresis

KW - Streptococcus pneumoniae

KW - Tetracycline resistant

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Trends of genetic relationship of serotype 23F penicillin-resistant streptococcus pneumoniae in Japan

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ASJC Scopus subject areas

UN SDG

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