Transient relief of asthma symptoms during jaundice: A possible beneficial role of bilirubin

Takashi Ohrui, Hiroyasu Yasuda, Mutsuo Yamaya, Toshifumi Matsui, Hidetada Sasaki

研究成果: Article査読

21 被引用数 (Scopus)

抄録

Bilirubin arises from enzymatic reduction by biliverdin reductase of biliverdin, a product of heme oxygenase activity. Recent literature describes that bilirubin is a major physiologic antioxidant that can protect cells from chemical oxidants such as hydrogen peroxide. Recently, it has been reported that oxidative stress may play a crucial role in the pathogenesis of asthma. We report a case of complete resolution of persistent difficult-to-control asthma in accordance with increased levels of serum bilirubin due to acute hepatitis B. The present case suggests that anti-oxidative agents might be effective for the treatment of asthma.

本文言語English
ページ(範囲)193-196
ページ数4
ジャーナルTohoku Journal of Experimental Medicine
199
3
DOI
出版ステータスPublished - 2003 3 1

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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