TY - JOUR
T1 - Transfusion-associated graft-versus-host disease in immunocompetent patient
T2 - Early diagnosis and therapy
AU - Sakurai, Masahiro
AU - Moizumi, Yoshimasa
AU - Uchida, Shigeharu
AU - Imai, Yoshimichi
AU - Tabayashi, Koichi
N1 - Copyright:
Copyright 2007 Elsevier B.V., All rights reserved.
PY - 1998/5
Y1 - 1998/5
N2 - We report a case of transfusion-associated graff-versus-host disease in a previously healthy, 68-year-old Japanese man following an emergency surgery for an acute aortic dissection. We confirmed the chimerism of lymphocytes and the effect of drug therapy using DNA polymorphism analysis. This method is a sensitive, convenient, and rapid method that it is also useful for the evaluation of therapy. And the combination therapy with methylprednisolone, cyclosporine, and 15-deoxyspergualin may be effective in treating transfusion-associated GVHD.
AB - We report a case of transfusion-associated graff-versus-host disease in a previously healthy, 68-year-old Japanese man following an emergency surgery for an acute aortic dissection. We confirmed the chimerism of lymphocytes and the effect of drug therapy using DNA polymorphism analysis. This method is a sensitive, convenient, and rapid method that it is also useful for the evaluation of therapy. And the combination therapy with methylprednisolone, cyclosporine, and 15-deoxyspergualin may be effective in treating transfusion-associated GVHD.
KW - 15-deoxyspergualin
KW - Polymorphism analysis of microsatellite DNA
KW - TA-GVHD
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U2 - 10.1002/(SICI)1096-8652(199805)58:1<84::AID-AJH17>3.0.CO;2-5
DO - 10.1002/(SICI)1096-8652(199805)58:1<84::AID-AJH17>3.0.CO;2-5
M3 - Article
C2 - 9590157
AN - SCOPUS:0031946833
VL - 58
SP - 84
EP - 86
JO - American Journal of Hematology
JF - American Journal of Hematology
SN - 0361-8609
IS - 1
ER -