抄録
Transcriptional activity of nuclei from human diploid fibroblast (WI‐38) cells at different passage levels was studied with endogenous RNA polymerase. The rate and extent of the RNA synthesis decreased when the nuclei were were prepared from senescent cells. The decreased activity of RNA synthesis in senescent cell nuclei was demonstrated from both the transcriptional assay and the estimation of the processing activity, i.e., polyadenylation of the transcripts.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 51-54 |
| ページ数 | 4 |
| ジャーナル | Journal of Cellular Physiology |
| 巻 | 102 |
| 号 | 1 |
| DOI | |
| 出版ステータス | Published - 1980 1月 |
| 外部発表 | はい |
ASJC Scopus subject areas
- 生理学
- 臨床生化学
- 細胞生物学