Toxic effects of selenodiglutathione on pregnant mice

Junzo Yonemoto, Tetsuro Hongo, Tsuguyoshi Suzuki, Akira Naganuma, Nobumasa Imura

研究成果: Article査読

9 被引用数 (Scopus)

抄録

A single dose of selenodiglutathione (GSSeSG) or sodium selenite (SS) was injected i.v. into pregnant CD-1 mice on day 12 of gestation at dosages varying from 16.4-32.0 μmol/kg body weight. Dose-dependent elevation of maternal death rates was observed for both treatments, and the slope of the dose-response curve was significantly steeper following GSSeSG treatment. However, fetotoxic effects were not different between the treatments.

本文言語English
ページ(範囲)35-39
ページ数5
ジャーナルToxicology Letters
21
1
DOI
出版ステータスPublished - 1984 4

ASJC Scopus subject areas

  • 毒物学

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