@article{0d7ca463be104680808b1caf2b90ae0c,
title = "Toward the total synthesis of Luminamicin: Construction of 14-membered lactone framework possessing versatile enol ether moiety",
abstract = "Luminamicin (1) was found to exhibit selective antibacterial activity against anaerobic bacteria by our group in 1985. The concise structure of 14-membered lactone of 1 was synthesized. Construction of a versatile enol ether moiety was achieved by Stille cross coupling via hydrostanylation of the ethynyl ether, and a maleic anhydride moiety was derived from the furan constitution by the oxidation after the macrolactonization at a late-stage.",
keywords = "14-Membered macrolactone, Antianaerobic activity, Coloradocin, Conjugated enol ether, Luminamicin",
author = "Aoi Kimishima and Tomoyasu Hirose and Akihiro Sugawara and Takanori Matsumaru and Kaoru Nakamura and Ken Katsuyama and Masaki Toda and Hirokazu Takada and Rokuro Masuma and Satoshi Omura and Toshiaki Sunazuka",
note = "Funding Information: This work was supported by a Grant for the 21st Century COE Program, Ministry of Education Culture, Sports, Science and Technology (MEXT) (Grant No. 18790022 ), a Grant-in-Aid for Scientific Research (Grant No. 16590012), Grant-in-Aid for Research Activity Start-up (Grant No. 22890175), the JSPS Research Fellowships for Young Scientists (T.M.), the Uehara Memorial Foundation (T.H.), and the Kitasato University Research Grant for Young Researchers (A.S.). We also thank Ms. A. Nakagawa and Ms. N. Sato (School of Pharmacy, Kitasato University) for various instrumental analyses. ",
year = "2012",
month = jun,
day = "6",
doi = "10.1016/j.tetlet.2012.03.098",
language = "English",
volume = "53",
pages = "2813--2816",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "23",
}