Tobacco smoking and gastric cancer risk: An evaluation based on a systematic review of epidemiologic evidence among the Japanese population

Yoshikazu Nishino, Manami Inoue, Ichiro Tsuji, Kenji Wakai, Chisato Nagata, Tetsuya Mizoue, Keitaro Tanaka, Shoichiro Tsugane

研究成果: Review article査読

94 被引用数 (Scopus)

抄録

Background: We evaluated the association between tobacco smoking and gastric cancer risk among the Japanese population based on a systematic review of epidemiologic evidence. Methods: Original data were collectedby searches of MEDLINE using PubMed, complemented with manual searches. Evaluation of associations was based on the strength of evidence and the magnitude of association, together with biological plausibility, as evaluated previously by the International Agency for Research on Cancer. Results: Ten cohort studies and 16 case-control studies were identified. In men, most studies reported moderate or strong positive associations between smoking and gastric cancer. In women, the positive association was weaker than in men. Of eight studies (three cohort studies and five case-case control studies), two cohort and three case control studies reported a weakly to strongly increased risk of gastric cancer. The summary relative risk for current smokers was estimated to be 1.56 (95% confidence intervals 1.36-1.80), 1.79 (1.51-2.12), 1.22 (1.07-1.38) for the total population, men and women, respectively. Conclusion: We conclude that there is convincing evidence that tobacco smoking moderately increases the risk of gastric cancer among the Japanese population.

本文言語English
ページ(範囲)800-807
ページ数8
ジャーナルJapanese journal of clinical oncology
36
12
DOI
出版ステータスPublished - 2006 12月

ASJC Scopus subject areas

  • 腫瘍学
  • 放射線学、核医学およびイメージング
  • 癌研究

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