Time course changes in cytoskeletal structures of cultured endothelial cells exposed to shear stress.

K. Ookawa, M. Sato, N. Ohshima

研究成果: Article査読

10 被引用数 (Scopus)

抄録

Changes in patterns of microfilament distribution were analyzed using cultured porcine aortic endothelial cells under shear flow. Within the elongated endothelial cells after shear flow exposure (20 dyne/cm2, 0-24 h), F-actin filaments were mainly observed as stress fibers. After 24 h exposure, the fluorescence intensity of rhodamine-phalloidin-stained cells was enhanced, indicating the increase in F-actin content. It was suggested that not only F-actin distribution but also the content may be affected by shear stress at the early stage of exposure.

本文言語English
ページ(範囲)121-125
ページ数5
ジャーナルFrontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering
5
2
出版ステータスPublished - 1993

ASJC Scopus subject areas

  • 生物理学

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