Therapeutic psychosocial intervention for elderly subjects with very mild Alzheimer disease in a community: The tajiri project

Junichi Ishizaki, Kenichi Meguro, Kyoko Ohe, Etsuko Kimura, Emiko Tsuchiya, Hiroshi Ishii, Yasuyoshi Sekita, Atsushi Yamadori

研究成果: Article査読

34 被引用数 (Scopus)

抄録

Elderly subjects with mild memory impairment but not apparent dementia are the focus of early intervention trials. To examine the effects of structural psychosocial intervention for elderly subjects with very mild Alzheimer disease, i.e., Clinical Dementia Rating 0.5. The design is a prospective study. The experimental group (14 Clinical Dementia Rating 0.5 subjects) and the control group (11 Clinical Dementia Rating 0.5 subjects) were studied. Subjects with cerebrovascular disease as shown by magnetic resonance imaging were excluded. The experimental group participated in activities in a day-care-like setting once a week over a period of 6 months, whereas the control group did not. Each group was reevaluated after approximately 9 months. The effects of intervention were evaluated by cognitive tests, affective scales, a global clinical measure, an observation scale in the sessions, and a projective test. The experimental group showed a significant improvement on the word fluency test, whereas the control group showed a significant decline on the Mini-Mental State Examination, the digit span, and the Trail Making-A test. The experimental group revealed significantly higher levels on the Mini-Mental State Examination and the digit span compared with the control group after the 6-month intervention. A significant improvement was found for the global clinical measure, the observation scale, and the projective test in the experimental group after the intervention. After controlling the potential confounders (age, educational level, baseline cognitive, and affective status) in a multiple regression analysis, the same results were found. We considered that psychosocial intervention had beneficial effects for subjects with very mild Alzheimer disease.

本文言語English
ページ(範囲)261-269
ページ数9
ジャーナルAlzheimer Disease and Associated Disorders
16
4
DOI
出版ステータスPublished - 2002 10月

ASJC Scopus subject areas

  • 臨床心理学
  • 老年学
  • 老年医学
  • 精神医学および精神衛生

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