The very low density lipoprotein receptor. A second lipoprotein receptor that may mediate uptake of fatty acids into muscle and fat cells

Tokuo Yamamoto, Sadao Takahashi, Juro Sakai, Yutaka Kawarabayasi

研究成果: Short survey査読

37 被引用数 (Scopus)

抄録

The isolation of a cDNA highly homologous to that of the low-density lipoprotein (LDL) receptor revealed the presence of a lipoprotein receptor that specifically binds apolipoprotein-E-containing lipoproteins, including very low density lipoprotein (VLDL), intermediate-density lipoprotein, and β-migrating VLDL. This new receptor, designated VLDL receptor, consists of five domains that resemble those of the LDL receptor. The VLDL receptor mRNA is abundant in tissues performing active fatty acid metabolism, suggesting that the receptor may be responsible for the uptake of fatty acids in triglyceride-rich lipoproteins into muscle and fat cells.

本文言語English
ページ(範囲)144-148
ページ数5
ジャーナルTrends in Cardiovascular Medicine
3
4
DOI
出版ステータスPublished - 1993 1 1

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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