The systemic inflammation-based Glasgow Prognostic Score as a prognostic factor in patients with acute heart failure

Shigeto Namiuchi, Tadashi Sugie, Kenya Saji, Toru Takii, Akira Suda, Atsushi Kato

研究成果: Article査読

18 被引用数 (Scopus)

抄録

Aims By combining C-reactive protein and serum albumin concentrations, the Glasgow Prognostic Score (GPS) provides valuable predictions of prognosis in patients with cancer. Both systemic inflammatory response and malnutrition are also common in patients with heart failure. We evaluated the efficacy of the GPS for predicting the prognoses of patients with acute decompensated heart failure (ADHF). Methods We investigated 336 patients who were admitted with ADHF. The GPS (0, 1, and 2) was defined as follows: patients with both elevated C-reactive protein (>1.0mg/dl) and hypoalbuminemia (<3.5g/dl) were allocated a score of 2, patients with only one of these biochemical abnormalities were allocated a score of 1, and patients with neither of these abnormalities were allocated a score of 0. Results During the follow-up period (mean±SD: 504±471 days), 71 patients (21.1%) died. Relative to a GPS of 0, the hazard ratios for all-cause death were 3.40 (95% confidence interval 1.81-6.45) for a GPS of 2 and 1.97 (95% confidence interval 1.06-3.66) for a GPS of 1, as determined using adjusted Cox proportional-hazards analysis. Conclusions The GPS, which is based on systemic inflammation, is useful for predicting the prognoses of hospitalized patients with ADHF.

本文言語English
ページ(範囲)409-415
ページ数7
ジャーナルJournal of Cardiovascular Medicine
16
6
DOI
出版ステータスPublished - 2015 6 6
外部発表はい

ASJC Scopus subject areas

  • 循環器および心血管医学

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