@article{c3b8e88da1324896a8b8fbc3c2279a6e,
title = "The synthesis of β-strand mimetic templates via regioselective 1,3-dipolar cycloaddition with vinylsulfone",
abstract = "We have developed a practical synthetic route to constrained β-strand mimetic templates by regioselective 1,3-dipolar cycloaddition of azomethine imines with vinyl sulfone. A small library of β-strand mimetic templates was generated which include potent and selective inhibitors of serine proteases.",
keywords = "1,3-Dipolar cycloaddition, Peptidomimetics, Serine protease inhibitor, Vinyl sulfone",
author = "Nobuhiro Fuchi and Takayuki Doi and Takeo Harada and Jan Urban and Bolong Cao and Michael Kahn and Takashi Takahashi",
year = "2001",
month = feb,
day = "12",
doi = "10.1016/S0040-4039(00)02229-2",
language = "English",
volume = "42",
pages = "1305--1308",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "7",
}