抄録
Rosacea is a common and chronic inflammatory skin disease that affects over 10 million Americans. Although the phenotypes of rosacea are clinically heterogeneous, they are all related by the presence of chronic facial skin inflammation. Until recently, the pathophysiology of this disease has been poorly understood and limited to descriptions of factors that exacerbate or improve this disorder. Recent molecular studies suggest that an altered innate immune response is involved in the pathogenesis of the vascular and inflammatory disease seen in patients with rosacea. These findings may help explain the benefits of current treatments and suggest new therapeutic strategies helpful for alleviating this disease. This article discusses the possible molecular mechanisms for the pathogenesis of rosacea from current clinical observations and laboratory research.
本文言語 | English |
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ページ(範囲) | 77-81 |
ページ数 | 5 |
ジャーナル | Journal of dermatological science |
巻 | 55 |
号 | 2 |
DOI | |
出版ステータス | Published - 2009 8月 |
外部発表 | はい |
ASJC Scopus subject areas
- 生化学
- 分子生物学
- 皮膚病学