The molecular pathology of rosacea

Kenshi Yamasaki, Richard L. Gallo

研究成果: Review article

198 引用 (Scopus)

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Rosacea is a common and chronic inflammatory skin disease that affects over 10 million Americans. Although the phenotypes of rosacea are clinically heterogeneous, they are all related by the presence of chronic facial skin inflammation. Until recently, the pathophysiology of this disease has been poorly understood and limited to descriptions of factors that exacerbate or improve this disorder. Recent molecular studies suggest that an altered innate immune response is involved in the pathogenesis of the vascular and inflammatory disease seen in patients with rosacea. These findings may help explain the benefits of current treatments and suggest new therapeutic strategies helpful for alleviating this disease. This article discusses the possible molecular mechanisms for the pathogenesis of rosacea from current clinical observations and laboratory research.

元の言語English
ページ(範囲)77-81
ページ数5
ジャーナルJournal of dermatological science
55
発行部数2
DOI
出版物ステータスPublished - 2009 8

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Dermatology

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