The first synthesis of chiral phosphinocarboxylic acid ligands, trans-2-(diphenylphosphino)cycloalkanecarboxylic acids. The phosphine-palladium complexes catalyzed asymmetric allylic alkylation

Yoshiharu Okada, Toru Minami, Yoritaka Sasaki, Yasuo Umezu, Masahiko Yamaguchi

研究成果: Article査読

32 被引用数 (Scopus)

抄録

The first synthesized chiral phosphinocarboxylic acids were effective as ligand for the palledium-catalyzed asymmetric allylic alkylation of 3-acetoxy-1,3-diphenyl-1-propene and 2-cyclohexenyl acetate with soft carbanion from dimethyl malonate or triethyl phosphonoacetate and sodium hydride to give the alkylation products of up to 83% ee.

本文言語English
ページ(範囲)3905-3908
ページ数4
ジャーナルTetrahedron Letters
31
27
DOI
出版ステータスPublished - 1990
外部発表はい

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

フィンガープリント 「The first synthesis of chiral phosphinocarboxylic acid ligands, trans-2-(diphenylphosphino)cycloalkanecarboxylic acids. The phosphine-palladium complexes catalyzed asymmetric allylic alkylation」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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