The first infant case with hepatosplenic γδ T-cell lymphoma after acute disseminated encephalomyelitis (ADEM)-like exacerbation

Shinichiro Y. Koga, Satoru Kumaki, Ryo Ichinohasama, Mitsutoshi Munakata, Kazuhiro Haginoya, Yoshiyuki Ohashi, Yoshiko Tanaka, Osamu Sakamoto, Masayoshi Minegishi, Tomohiro Morio, Kazuie Iinuma, Shigeru Tsuchiya

研究成果: Article査読

2 被引用数 (Scopus)

抄録

We report the first infant case with hepatosplenic γδ T-cell lymphoma after recurrent acute disseminated encephalomyelitis-like, which were rapidly resolved with steroid pulse therapy. The patient had a history of recurrent bronchitis, intractable diarrhea, and failure to thrive since 4 months of age. Immunologic analysis revealed higher percentage of circulating γδ T-cells with markedly reduced numbers of CD3TCRαβCD8 T-cells. The patient developed γδ T-cell lymphoma at the age of 15 months. Clinical course of the patient suggests the importance of immunological background for the development of hepatosplenic γδ T-cell lymphoma.

本文言語English
ページ(範囲)741-745
ページ数5
ジャーナルJournal of Pediatric Hematology/Oncology
28
11
DOI
出版ステータスPublished - 2006 11

ASJC Scopus subject areas

  • 小児科学、周産期医学および子どもの健康
  • 血液学
  • 腫瘍学

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