We report the first infant case with hepatosplenic γδ T-cell lymphoma after recurrent acute disseminated encephalomyelitis-like, which were rapidly resolved with steroid pulse therapy. The patient had a history of recurrent bronchitis, intractable diarrhea, and failure to thrive since 4 months of age. Immunologic analysis revealed higher percentage of circulating γδ T-cells with markedly reduced numbers of CD3TCRαβCD8 T-cells. The patient developed γδ T-cell lymphoma at the age of 15 months. Clinical course of the patient suggests the importance of immunological background for the development of hepatosplenic γδ T-cell lymphoma.
|ジャーナル||Journal of Pediatric Hematology/Oncology|
|出版ステータス||Published - 2006 11|
ASJC Scopus subject areas