The efficacy of lung cancer screening in Miyagi Prefecture, Japan: A comparison of 2 case-control studies conducted in the 1980s and in the 1990s

M. Sagawa, Y. Saito, M. Sato, S. Takahashi, K. Usuda, A. Sakurada, C. Endo, H. Takahashi, T. Kondo, T. Sakuma

研究成果: Article査読

抄録

Objective: To evaluate the efficacy of lung cancer screening. Methods: In Miyagi Prefecture, Japan, 2 case-control studies to evaluate the efficacy of lung cancer screening were conducted independently in 1988-90 and in 1997-99. We compared the differences in the methods and the results between the two studies. Results: The smoking-adjusted odds ratios were 0.55 in the 1980s (62 cases and 285 controls) and 0.54 in the 1990s (328 cases and 1886 controls), respectively. After excluding sets from the 1990s-study to imitate the conditions of the 1980s-study, the odds ratio of dying from lung cancer in the 1990s changed to 0.27-0.46. Conclusion: The mass screening program for lung cancer reduced the risk for lung cancer death in both case-control studies. The self-selection bias and/or the improvement of diagnostic/therapeutic modality for lung cancer might influence the results in the two studies.

本文言語English
ページ(範囲)299-303
ページ数5
ジャーナルJapanese Journal of Lung Cancer
41
4
DOI
出版ステータスPublished - 2001

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine

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