The coexistence of Alzheimer's disease and Creutzfeldt-Jakob disease in a patient with dementia of long duration

T. Muramoto, T. Kitamoto, H. Koga, J. Tateishi

研究成果: Article査読

40 被引用数 (Scopus)

抄録

We report here a 75-year-old-male with a slowly progressive dementia of 5-year duration along with a rapid exacerbation of symptoms in the terminal 3 months. Neuropathological examinations revealed findings consistent with conspicuous Alzheimer's disease and mild Creutzfeldt-Jakob disease (CJD). The plaque amyloid was exclusively composed of β-protein. The immunohistochemistry of prion protein using hydrolytic autoclaving pretreatment showed diffuse gray matter stainings in the sections of both the cerebral and cerebellar cortices. This method was thus considered useful in confirming the diagnosis of CJD for this case.

本文言語English
ページ(範囲)686-689
ページ数4
ジャーナルActa neuropathologica
84
6
DOI
出版ステータスPublished - 1992 11月 1
外部発表はい

ASJC Scopus subject areas

  • 病理学および法医学
  • 臨床神経学
  • 細胞および分子神経科学

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