The amount and pattern of DNA polymorphism under the neutral mutation hypothesis

Fumio Tajima, Kazuharu Misawa, Hideki Innan

研究成果: Article査読

6 被引用数 (Scopus)

抄録

The amount and pattern of DNA polymorphism can give useful information on the maintenance mechanism of genetic variation at the DNA level. In this note we have shown the amount and pattern of DNA polymorphism expected under the neutral theory. The amount of DNA polymorphism can be estimated from the average number of nucleotide differences per site, the proportion of segregating sites, and so on. We have shown how to estimate 0 from these quantities, where Θ = 4Nv, N is the effective population size and v is the mutation rate per site per generation. We have also shown the expectations of the nucleotide variation within and between allelic classes.

本文言語English
ページ(範囲)103-107
ページ数5
ジャーナルGenetica
102-103
DOI
出版ステータスPublished - 1998

ASJC Scopus subject areas

  • 動物科学および動物学
  • 遺伝学
  • 植物科学
  • 昆虫科学

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