The 2011 Tohoku-Oki Earthquake (M9.0) significantly affected inland areas of Japan. The crust and mantle response to the magathrust earthquake induced changes in the mechanical conditions of the seismo-genic zone. Here we present important progress in the research into the seismogenesis of inland earthquakes. Stress, strain, strength, and structures are key parameters affecting the occurrence of earthquakes. In par-ticular, both the spatial and temporal changes in these parameters around the focal areas of the large inland earthquakes have been detected and modeled. These results have provided spatial potential evaluation in terms of future inland earthquake occurrence. How-ever, we clearly recognize that, in order to understand and predict the inland earthquake generation process, it will inevitably be necessary to unify the research on various spatial and temporal scales, from problems related to long-term stress loading from plate-relative motion to instant fault response.
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