Targeting selective autophagy by AUTAC degraders

研究成果: Comment/debate査読

8 被引用数 (Scopus)

抄録

Targeted degradation is a promising new modality in drug discovery that makes it possible to reduce intracellular protein levels with small molecules. It is a complementary approach to the conventional protein knockdown typically used in laboratories and may offer a way to approach the currently undruggable human proteome. Recently, the first autophagy-mediated degraders, called AUTACs, were developed based on observations in a xenophagy study.

本文言語English
ページ(範囲)765-766
ページ数2
ジャーナルAutophagy
16
4
DOI
出版ステータスPublished - 2020 4 2

ASJC Scopus subject areas

  • 分子生物学
  • 細胞生物学

フィンガープリント

「Targeting selective autophagy by AUTAC degraders」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル