T-cell lymphoma presenting neutrophilic inflammation in the cerebrospinal fluid

Takaaki Nakamura, Yoshiki Takai, Kimihiko Kaneko, Hiroshi Kuroda, Tatsuro Misu, Kiyotaka Asanuma, Ryoko Saito, Masashi Aoki

研究成果: Article査読

抄録

A 66-year-old woman presented with upper abdominal pain and weakness in the limbs. She had bilateral uveitis and gastric ulcers. A neurological examination revealed tetraparesis and sensory disturbance in the right arm. A cerebrospinal fluid (CSF) examination showed polymorphonuclear pleocytosis with elevated proinflammatory cytokine levels. Magnetic resonance imaging showed brain lesions and a long spinal cord lesion. She was initially diagnosed with neuro-Behçet's disease and was treated with corticosteroids, resulting in no improvement. A gastric mucosa biopsy indicated T-cell lymphoma colocalizing with neutrophils. The cytokine-mediated neutrophilic inflammation probably caused characteristic CSF and histopathological features. It is noteworthy that T-cell lymphoma may present with CSF neutrophilic inflammation.

本文言語English
ページ(範囲)573-576
ページ数4
ジャーナルInternal Medicine
59
4
DOI
出版ステータスPublished - 2020 2 15

ASJC Scopus subject areas

  • 内科学

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