Systems biology model repository for macrophage pathway simulation

Masao Nagasaki; Ayumu Saito; André Fujita; Georg Tremmel; Kazuko Ueno; Emi Ikeda; Euna Jeong; Satoru Miyano

doi:10.1093/bioinformatics/btr173

Systems biology model repository for macrophage pathway simulation

Masao Nagasaki, Ayumu Saito, André Fujita, Georg Tremmel, Kazuko Ueno, Emi Ikeda, Euna Jeong, Satoru Miyano

東北メディカル・メガバンク機構

研究成果: Article › 査読

4 被引用数 (Scopus)

抄録

The Macrophage Pathway Knowledgebase (MACPAK) is a computational system that allows biomedical researchers to query and study the dynamic behaviors of macrophage molecular pathways. It integrates the knowledge of 230 reviews that were carefully checked by specialists for their accuracy and then converted to 230 dynamic mathematical pathway models. MACPAK comprises a total of 24009 entities and 12774 processes and is described in the Cell System Markup Language (CSML), an XML format that runs on the Cell Illustrator platform and can be visualized with a customized Cytoscape for further analysis.

本文言語	English
論文番号	btr173
ページ（範囲）	1591-1593
ページ数	3
ジャーナル	Bioinformatics
巻	27
号	11
DOI	https://doi.org/10.1093/bioinformatics/btr173
出版ステータス	Published - 2011 6月

ASJC Scopus subject areas

統計学および確率
生化学
分子生物学
コンピュータサイエンスの応用
計算理論と計算数学
計算数学

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10.1093/bioinformatics/btr173

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AU - Fujita, André

AU - Tremmel, Georg

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AU - Jeong, Euna

AU - Miyano, Satoru

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Systems biology model repository for macrophage pathway simulation

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ASJC Scopus subject areas

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