Systems biology approaches in breast cancer studies

Zhiwei Wang, Shavali Shaik, Hiroyuki Inuzuka, Wenyi Wei

研究成果: Chapter

1 被引用数 (Scopus)

抄録

Breast cancer is the second most common malignancy for women. Currently, only several prognostic and predictive factors are used clinically for managing breast cancer patients. Recently, systems biology approaches based on high-throughput technologies such as DNA microarrays, mass spectrometry-based proteomics and metabolomics have began to be used to investigate the expression of a wide range of genes and proteins in the dissected breast tumors. Moreover, these expression signatures have been found to provide potential and independent prognostic information in patients diagnosed with breast cancer. Furthermore, these molecular signatures could not only help to identify new therapeutic targets, but also allow physicians to design more effective and targeted therapeutic strategies for achieving better treatment outcomes of breast cancer patients.

本文言語English
ホスト出版物のタイトルBreast Cancer Metastasis and Drug Resistance
ホスト出版物のサブタイトルProgress and Prospects
出版社Springer New York
ページ329-340
ページ数12
9781461456476
ISBN(電子版)9781461456476
ISBN(印刷版)1461456460, 9781461456469
DOI
出版ステータスPublished - 2013 8月 1
外部発表はい

ASJC Scopus subject areas

  • 医学(全般)

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