抄録
A synthetic route to the FGH ring system of gambierol, a marine polyether toxin isolated from the dinoflagellate Gambierdiscus toxicus, has been developed. The present synthesis features B-alkyl Suzuki coupling of the F and H rings, followed by ring-closure of the G ring and stereoselective installation of 1,3-diaxial methyl groups at C21 and C23. (C) 2000 Elsevier Science Ltd.
本文言語 | English |
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ページ(範囲) | 8371-8375 |
ページ数 | 5 |
ジャーナル | Tetrahedron Letters |
巻 | 41 |
号 | 43 |
DOI | |
出版ステータス | Published - 2000 10 21 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry