Synthetic studies on a marine polyether toxin, gambierol: Stereoselective synthesis of the FGH ring system via B-alkyl Suzuki coupling

H. Fuwa, M. Sasaki, K. Tachibana

    研究成果: Article査読

    58 被引用数 (Scopus)

    抄録

    A synthetic route to the FGH ring system of gambierol, a marine polyether toxin isolated from the dinoflagellate Gambierdiscus toxicus, has been developed. The present synthesis features B-alkyl Suzuki coupling of the F and H rings, followed by ring-closure of the G ring and stereoselective installation of 1,3-diaxial methyl groups at C21 and C23. (C) 2000 Elsevier Science Ltd.

    本文言語English
    ページ(範囲)8371-8375
    ページ数5
    ジャーナルTetrahedron Letters
    41
    43
    DOI
    出版ステータスPublished - 2000 10 21

    ASJC Scopus subject areas

    • Biochemistry
    • Drug Discovery
    • Organic Chemistry

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