Synthesis of trisubstituted allenamides utilizing 1,2-rearrangement of dialkoxyphosphoryl moiety under Brønsted base catalysis

研究成果: Article査読

2 被引用数 (Scopus)

抄録

A new method for the synthesis of trisubstituted allenamides was developed by utilizing the 1,2-rearrangement of a dialkoxyphosphoryl moiety from carbon to nitrogen under Brønsted base catalysis. The reaction would involve the catalytic generation of an α-amino propargyl anion through the key rearrangement, the addition to an electrophile at the α-position of the anionic intermediate, and the unprecedented rearrangement of a phosphoramidate moiety of the adduct, providing trisubstituted allenamides that are difficult to synthesize by using conventional methods.

本文言語English
ページ(範囲)1164-1167
ページ数4
ジャーナルChemistry Letters
48
9
DOI
出版ステータスPublished - 2019

ASJC Scopus subject areas

  • Chemistry(all)

フィンガープリント 「Synthesis of trisubstituted allenamides utilizing 1,2-rearrangement of dialkoxyphosphoryl moiety under Brønsted base catalysis」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル