Polyketides, biosynthetic intermediates of natural aromatic compounds, are useful in organic synthesis. Various polyketides were prepared by using the Claisen- type reaction of polyanions of β- ketoesters, and the intramolecular condensation to give aromatic compounds were examined. Based on the studies, a new synthetic method for the polycyclic aromatic compounds was developed. The process allows the synthesis of polyoxygenated naphthalene, anthracene, naphthacene, and pentacene derivatives.
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