Synthesis of di-branched heptasaccharide by one-pot glycosylation using seven independent building blocks

Hiroshi Tanaka, Masaatsu Adachi, Hirokazu Tsukamoto, Takeji Ikeda, Haruo Yamada, Takashi Takahashi

研究成果: Article査読

78 被引用数 (Scopus)

抄録

(Equation presented) We describe an efficient synthesis of di-branched heptasaccharide 1 having phytoalexin elicitor activity in soybeans by one-pot glycosylation. The synthesis involves chemo-and regioselective sequential six-step glycosylations using seven independent building blocks and sequential removal of acyl-and benzyl ether-type protecting groups. The coupling of seven building blocks requires only four chemoselective activitable leaving groups of glycosyl donors. Both the glycosylation and deprotection reactions can be achieved utilizing a parallel manual synthesizer.

本文言語English
ページ(範囲)4213-4216
ページ数4
ジャーナルOrganic letters
4
24
DOI
出版ステータスPublished - 2002 11月 28

ASJC Scopus subject areas

  • 生化学
  • 物理化学および理論化学
  • 有機化学

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