Synthesis of cyclopent-2-enones through stepwise [3 + 2] cycloaddition of simple silyl enol ethers and alk-1-ynes

Masahiko Yamaguchi, Michiru Sehata, Akio Hayashi, Masahiro Hirama

研究成果: Article査読

11 被引用数 (Scopus)

抄録

Treatment of silyl enol ethers and alk-1-ynes with SnCl4-Bu 3N reagent followed by DBU, leads to cyclopent-2-enones, through [3 + 2] cycloaddition reactions; the initial carbon-carbon bond formation is carbometallation of alkynes, and the second step is a base-promoted intramolecular alkylation which reductively eliminates tin species (DBU = 1,8-diazabicyclo[5.4.0]undec-7-ene).

本文言語English
ページ(範囲)1708-1709
ページ数2
ジャーナルJournal of the Chemical Society, Chemical Communications
22
DOI
出版ステータスPublished - 1993
外部発表はい

ASJC Scopus subject areas

  • 分子医療

フィンガープリント

「Synthesis of cyclopent-2-enones through stepwise [3 + 2] cycloaddition of simple silyl enol ethers and alk-1-ynes」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル