Synthesis of 4,7′-Bibenzo[ b ]thiophenes Bearing Several Different Substituents at 2-, 2′-, 4′-, and 7-Positions; Structurally Featured Molecular Scaffolds for Selective Substitution

Shinichi Mikami, Akihiro Matsuo, Eunsang Kwon, Kozo Toyota

研究成果: Article査読

抄録

Four isomers of 4,7'-bibenzothiophene scaffolds bearing two different halogen (Br, Cl) and triisopropylsilyl substituents have been synthesized from the two multihalobenzo[b]thiophenes via iodoselective Miyaura borylation reaction using potassium benzoate as a base. Further investigation into the reactivity of 4,7'-bibenzothiophenes in substitution reaction, Suzuki Miyaura cross-coupling reaction, and C-H direct arylation reaction revealed that tetrasubstituted 4,7'-bibenzothiophenes can be synthesized site- (chemo-) selectively, which are promising novel components for molecular architecture.

本文言語English
論文番号st-2021-u0294-l
ページ(範囲)1826-1832
ページ数7
ジャーナルSynlett
32
18
DOI
出版ステータスPublished - 2021 11

ASJC Scopus subject areas

  • 有機化学

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「Synthesis of 4,7′-Bibenzo[ b ]thiophenes Bearing Several Different Substituents at 2-, 2′-, 4′-, and 7-Positions; Structurally Featured Molecular Scaffolds for Selective Substitution」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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