Synthesis and biological evaluation of 9-(t-2, c-3-bishydroxymethyl-r-1-cyclopropylmethyl)-9h-adenine (a lower methylene homolog of carbocyclic oxetanocin) and related compounds.1)

Nobuya Katagiri, Hiroshi Sato, Chikara Kaneko

研究成果: Article査読

18 被引用数 (Scopus)

抄録

Adenine (7 and 16). thymine (9a and 18a). and 5-fluorouracil (9b and 18b) involving t-2, c-3-bishydroxymethyl-r-1-cyclopropylmethyl- and t-2, t-3-bishydroxymethyl-r-1-cyclopropylmethyl residues were synthesized, starting from trans-t, 4-dibenzyloxy-2-butene and its cis isomer, respectively. These compounds were evaluated for anti HSV-1 activity.

本文言語English
ページ(範囲)707-718
ページ数12
ジャーナルNucleosides and Nucleotides
11
2-4
DOI
出版ステータスPublished - 1992 2月 1
外部発表はい

ASJC Scopus subject areas

  • 生化学
  • 遺伝学

フィンガープリント

「Synthesis and biological evaluation of 9-(t-2, c-3-bishydroxymethyl-r-1-cyclopropylmethyl)-9h-adenine (a lower methylene homolog of carbocyclic oxetanocin) and related compounds.1)」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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