Synchronized and timing-stabilized pulse generation from a gain-switched laser diode for stimulated Raman scattering microscopy

Kyoya Tokunaga, Yi Cheng Fang, Hiroyuki Yokoyama, Yasuyuki Ozeki

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

We present a picosecond laser source based on a gain-switched laser diode (GS-LD) that can be applied to stimulated Raman scattering (SRS) microscopy. A 1.06-μm GS-LD was used to generate 14-ps pulses at a repetition rate of 38 MHz. The GS-LD was driven by 200-ps electrical pulses, which were triggered through a toggle flip-flop (T-FF). As a result, the GS-LD pulses were subharmonically synchronized to Ti:sapphire laser (TSL) pulses at a repetition rate of 76 MHz. We investigated the timing jitter of GS-LD pulses and found it to be less than 2.5 ps. We also show that the trigger delay can be less sensitive to the optical power of TSL pulses by controlling the threshold voltage of the T-FF. As a result, GS-LD pulses sufficiently overlapped with TSL pulses even when we scanned the wavelength of the TSL pulses. We demonstrate the SRS imaging of HeLa cells with GS-LD pulses and TSL pulses, proving that GS-LD is readily applicable to SRS microscopy as a compact and stable pulse source.

本文言語English
ホスト出版物のタイトルMultiphoton Microscopy in the Biomedical Sciences XVI
編集者Peter T. C. So, Karsten Konig, Ammasi Periasamy, Karsten Konig
出版社SPIE
ISBN(電子版)9781628419467
DOI
出版ステータスPublished - 2016
イベントMultiphoton Microscopy in the Biomedical Sciences XVI - San Francisco, United States
継続期間: 2016 2 142016 2 16

出版物シリーズ

名前Progress in Biomedical Optics and Imaging - Proceedings of SPIE
9712
ISSN(印刷版)1605-7422

Other

OtherMultiphoton Microscopy in the Biomedical Sciences XVI
国/地域United States
CitySan Francisco
Period16/2/1416/2/16

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 生体材料
  • 原子分子物理学および光学
  • 放射線学、核医学およびイメージング

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