TY - JOUR
T1 - Surface-Restructuring Differences between Polyrotaxanes and Random Copolymers in Aqueous Environment
AU - Ge, Aimin
AU - Qiao, Lin
AU - Seo, Ji Hun
AU - Yui, Nobuhiko
AU - Ye, Shen
N1 - Funding Information:
This research is partly supported by a Grant-in-Aid for Scientific Research (B) 17H01879 from the Ministry of Education, Culture, Sports, Science & Technology (MEXT), Japan. N.Y. acknowledges a Grant-in-Aid for Scientific Research (A) 16H01852 from MEXT, Japan.
Publisher Copyright:
© 2018 American Chemical Society.
PY - 2018/10/16
Y1 - 2018/10/16
N2 - In the present study, we investigated the surface reorganization behaviors and adsorption conformations of fibrinogen on the surface of polyrotaxanes containing different amounts of α-cyclodextrin (α-CD) by using surface-sensitive vibrational spectroscopy sum frequency generation (SFG). For comparison, behaviors of the surface restructuring and fibrinogen adsorption on the random copolymers containing similar terminal groups were also investigated. It was found that larger amounts of BMA moieties of polyrotaxanes form ordered surface structures after immersion in water for 48 h. Furthermore, the polyrotaxane surfaces exhibit a much higher capability of fibrinogen adsorption than the random copolymer surfaces. The water-induced surface restructuring of the polyrotaxane films slightly affects the adsorption structure of the fibrinogen molecules.
AB - In the present study, we investigated the surface reorganization behaviors and adsorption conformations of fibrinogen on the surface of polyrotaxanes containing different amounts of α-cyclodextrin (α-CD) by using surface-sensitive vibrational spectroscopy sum frequency generation (SFG). For comparison, behaviors of the surface restructuring and fibrinogen adsorption on the random copolymers containing similar terminal groups were also investigated. It was found that larger amounts of BMA moieties of polyrotaxanes form ordered surface structures after immersion in water for 48 h. Furthermore, the polyrotaxane surfaces exhibit a much higher capability of fibrinogen adsorption than the random copolymer surfaces. The water-induced surface restructuring of the polyrotaxane films slightly affects the adsorption structure of the fibrinogen molecules.
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U2 - 10.1021/acs.langmuir.8b02676
DO - 10.1021/acs.langmuir.8b02676
M3 - Article
C2 - 30216076
AN - SCOPUS:85054387336
VL - 34
SP - 12463
EP - 12470
JO - Langmuir
JF - Langmuir
SN - 0743-7463
IS - 41
ER -