Surface plasmon resonance imaging of Au nano-partifcle modified DNA monolayers

Akira Yamaguchi, Masayuki Hayashida, Saulius Juodkazis, Yoichiro Hara, Shigeki Matsuo, Hiroaki Misawa

研究成果: Article査読

抄録

A probe DNA monolayer modified with Au nano-particles was prepared on an Au thin film and used for DNA hybridization detection by surface plasmon resonance (SPR) spectroscopy. This Au particle modified probe DNA monolayer resulted in about a 3.5 times larger SPR angle shift according to the hybridization reaction, compared to that found in a non-modified probe DNA monolayer. By comparison of the SPR image of the particle modified and non-modified probe DNA monolayer, this modification method was shown to be useful in improving the SPR signal for the detection of the unlabelled DNA molecules.

本文言語English
ページ(範囲)247-251
ページ数5
ジャーナルUnknown Journal
4626
DOI
出版ステータスPublished - 2002

ASJC Scopus subject areas

  • 電子工学および電気工学
  • 凝縮系物理学

フィンガープリント

「Surface plasmon resonance imaging of Au nano-partifcle modified DNA monolayers」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル