Suppression of anodal break excitation by electrical stimulation with down-staircase waveform for distance-selective nerve recruitment

Ayako Ueno, Akihiro Karashima, Mitsuyuki Nakao, Norihiro Katayama

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

Electrical nerve stimulation using extracellular electrodes is widely performed in clinical medicine as well as basic medical science. It has been reported that selective recruitment of nerve fibers on the basis of the distance between the electrode and the axon is possible without moving the electrode and only by modifying the waveform of electrical stimulation. However, computer simulations have not reproduced the complete nature of the distance-selectivity of the stimulus owing to the difficulty in numerical analysis. In this paper, we propose a minor modification to the myelinated axon model to overcome this difficulty. We confirm that this modification improves the numerical stability of the simulation and enables us to obtain the spatio-temporal dynamics of axons, including the electrode-to-axon distance-dependency. In addition, we propose a novel stimulation method using a down-staircase waveform for distance-selective nerve recruitment. Simulations confirm that the method works well. We show the spatial distribution of axons activated by the down-staircase stimulation, which would be helpful to determine the stimulation parameters for distance-selective nerve recruitment.

本文言語English
ホスト出版物のタイトル2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2012
ページ211-214
ページ数4
DOI
出版ステータスPublished - 2012
イベント34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012 - San Diego, CA, United States
継続期間: 2012 8月 282012 9月 1

出版物シリーズ

名前Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN(印刷版)1557-170X

Other

Other34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012
国/地域United States
CitySan Diego, CA
Period12/8/2812/9/1

ASJC Scopus subject areas

  • 信号処理
  • 生体医工学
  • コンピュータ ビジョンおよびパターン認識
  • 健康情報学

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