Muscle contraction results from relative sliding of actin and myosin filaments. However, the possibility that actin filaments twist or rotate during sliding has not yet been experimentally investigated. We found that a super helix of an actin filament is formed in an in vitro motile system. This fact suggests that an actin filament twists and rotates due to a torque component of a sliding force generated at cross-bridges.
|ジャーナル||Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular|
|出版ステータス||Published - 1992 9 4|
ASJC Scopus subject areas
- Structural Biology
- Molecular Biology