15N-15N J-coupling across HgII: Direct observation of HgII-mediated T-T base pairs in a DNA duplex

Yoshiyuki Tanaka, Shuji Oda, Hiroshi Yamaguchi, Yoshinori Kondo, Chojiro Kojima, Akira Ono

研究成果: Article査読

446 被引用数 (Scopus)

抄録

N-N J-coupling across a metal center (2JNN) was clearly detected in a biological macromolecule (DNA duplex) for the first time. By using 2JNN, the base pairing mode of mercury-mediatedT-T pairs (T-HgII-T) was definitely determined. This pairing mode was found to be a novel metal ion-binding mode for DNA and RNA molecules, in which imino proton-metal exchange processes are included. Accordingly, 2JNN is highly important for the determination of the chemical structures of metal-mediated base pairs.

本文言語English
ページ(範囲)244-245
ページ数2
ジャーナルJournal of the American Chemical Society
129
2
DOI
出版ステータスPublished - 2007 1 17

ASJC Scopus subject areas

  • 触媒
  • 化学 (全般)
  • 生化学
  • コロイド化学および表面化学

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