TY - JOUR
T1 - Subcellular organelle analysis applying confocal laser scanning microscopy to the steroid-producing epithelial ovarian tumor
T2 - A technical note
AU - Yasuda, Masanori
AU - Itoh, Johbu
AU - Muramatsu, Toshinari
AU - Shinozuka, Takao
AU - Sasano, Hironobu
AU - Tsutsumi, Yutaka
AU - Osamura, R. Yoshiyuki
PY - 1997
Y1 - 1997
N2 - An epithelial ovarian tumor with steroid production was examined in a 70-year-old postmenopausal female. The stromal cells of this tumor were rather dense and occasionally characterized by luteinization or hyperthecosis, which has been associated with steroidogenesis. Subcellular visualization using confocal laser scanning microscopy (CLSM) successfully led to the identification of 3β-hydroxysteroid dehydrogenase (HSD) in both mitochondria-like small particles and endoplasmic reticulum-like linear profiles, and P450-aromatase also in endoplasmic reticulum-like linear profiles, on the three-dimensional images.
AB - An epithelial ovarian tumor with steroid production was examined in a 70-year-old postmenopausal female. The stromal cells of this tumor were rather dense and occasionally characterized by luteinization or hyperthecosis, which has been associated with steroidogenesis. Subcellular visualization using confocal laser scanning microscopy (CLSM) successfully led to the identification of 3β-hydroxysteroid dehydrogenase (HSD) in both mitochondria-like small particles and endoplasmic reticulum-like linear profiles, and P450-aromatase also in endoplasmic reticulum-like linear profiles, on the three-dimensional images.
KW - confocal laser scanning microscopy
KW - epithelial ovarian tumor
KW - steroidogenic stroma
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U2 - 10.1111/j.1440-1827.1997.tb04505.x
DO - 10.1111/j.1440-1827.1997.tb04505.x
M3 - Article
C2 - 9143033
AN - SCOPUS:0030903156
VL - 47
SP - 336
EP - 338
JO - Acta Pathologica Japonica
JF - Acta Pathologica Japonica
SN - 1320-5463
IS - 5
ER -