Sub-piconewton force fluctuations of actomyosin in vitro

Akihiko Ishijima, Takashi Doi, Katsuhiko Sakurada, Toshio Yanagida

研究成果: Article査読

206 被引用数 (Scopus)

抄録

A new system has been developed for measuring the forces produced by a small number (<5-150) of myosin molecules interacting with a single actin filament in vitro. The technique can resolve forces of less than a piconewton and has a time resolution in the submillisecond range. It can thus detect fluctuations of force caused by individual molecular interactions. From analysis of these force fluctuations, the coupling between the enzymatic ATPase activity of actomyosin and the resulting mechanical impulses can be elucidated.

本文言語English
ページ(範囲)301-306
ページ数6
ジャーナルNature
352
6333
DOI
出版ステータスPublished - 1991

ASJC Scopus subject areas

  • 一般

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