Studies toward the total synthesis of gambieric acids: Stereocontrolled synthesis of a DEFG-ring model compound

Haruhiko Fuwa, Sayaka Noji, Makoto Sasaki

    研究成果: Article査読

    14 被引用数 (Scopus)

    抄録

    (Figure presented) A stereocontrolled convergent synthesis of a DEFG-ring model compound of gambieric acids, highly potent antifungal marine polycyclic ether natural products, has been achieved based on Suzuki- Miyaura coupling. Conformational analysis of the model compound revealed that the nine-membered F-ring exists exclusively as a single stable conformer, as opposed to that of ciguatoxins.

    本文言語English
    ページ(範囲)5072-5082
    ページ数11
    ジャーナルJournal of Organic Chemistry
    75
    15
    DOI
    出版ステータスPublished - 2010 8 6

    ASJC Scopus subject areas

    • Organic Chemistry

    フィンガープリント 「Studies toward the total synthesis of gambieric acids: Stereocontrolled synthesis of a DEFG-ring model compound」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

    引用スタイル