Studies on Uricosuric Diuretics: III: Substituted l,3-Dioxolo[4,5-/]-l,2-benzisoxazole-6-carboxylic Acids and l^-DioxoloJ^S-g^-l^-benzisoxazole-T-carboxylic Acids1)

Haruhiko Sato, Takashi Dan, Etsuro Onuma, Haruko Tanaka, Bunya Aoki, Hiroshi Koga

研究成果: Article査読

6 被引用数 (Scopus)

抄録

A series of substituted 1,3-dioxolo[4,5-/]-l, 2-benzisoxazole-6-carboxylic acids 13 and l,3-dioxolo[4,5-#]-l,2-benzisoxazole-7-carboxylic acids 14 were synthesized and evaluated for diuretic and uricosuric activities in rats. Most of the benzisoxazole derivatives 13 and 14 showed potent diuretic activities. Moderate uricosuric activities were also found in 14a, 14b, and 14f.

本文言語English
ページ(範囲)109-116
ページ数8
ジャーナルChemical and Pharmaceutical Bulletin
40
1
DOI
出版ステータスPublished - 1992

ASJC Scopus subject areas

  • 化学 (全般)
  • 創薬

フィンガープリント

「Studies on Uricosuric Diuretics: III: Substituted l,3-Dioxolo[4,5-/]-l,2-benzisoxazole-6-carboxylic Acids and l^-DioxoloJ^S-g^-l^-benzisoxazole-T-carboxylic Acids1)」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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