@article{eb1f911c7ac1496bb204f8a2d74fd021,
title = "Stereoselective conjugate addition of ketones to alkylidene malonates using thiourea-sulfonamide organocatalyst",
abstract = "In this study, stereoselective conjugate addition of ketones to alkylidene malonates using organocatalyst has been developed. The reaction in the presence of 20 mol% of a novel thiourea-sulfonamide organocatalyst afforded conjugate adducts in moderate to high yields (up to 81%) under mild reaction conditions. Excellent diastereoselectivity (up to 98:2 dr) and enantioselectivity (up to 88% ee) were achieved.",
keywords = "alkylidene malonate, asymmetric conjugate addition, organocatalysis, organocatalyst, thiourea-sulfonamideIntroduction",
author = "Masahiro Kawada and Kosuke Nakashima and Hirashima, {Shin ichi} and Toru Sakagami and Yuji Koseki and Tsuyoshi Miura",
note = "Funding Information: This work was supported by JSPS KAKENHI Grant Number 16K08178. The authors would like to thank Enago (WWW.ENAGO.JP) for the English language review. Publisher Copyright: {\textcopyright} 2018 Wiley Periodicals, Inc.",
year = "2018",
month = nov,
doi = "10.1002/chir.23015",
language = "English",
volume = "30",
pages = "1215--1224",
journal = "Chirality",
issn = "0899-0042",
publisher = "Wiley-Liss Inc.",
number = "11",
}