Sporadic Creutzfeldt-Jakob disease with MM1-type prion protein and plaques

Chiho Ishida, A. Kakishima, S. Okino, Y. Furukawa, M. Kano, Y. Oda, I. Nakanishi, T. Makifuchi, T. Kitamoto, M. Yamada

研究成果: Article

16 被引用数 (Scopus)

抄録

The authors report a 75-year-old woman with atypical sporadic Creutzfeldt-Jakob disease (CJD) characterized by MM1-type prion protein (PrP) (methionine homozygosity at codon 129 in the PrP gene and type-1 protease-resistant PrP) and PrP plaques. This patient is the first case of sporadic CJD with plaque-forming MM1-type PrP, suggesting either a shared prion strain with the plaque-forming subset of dural graft-associated CJD or shared host genetic factors that are unrelated to the PrP genotype.

本文言語English
ページ(範囲)514-517
ページ数4
ジャーナルNeurology
60
3
DOI
出版ステータスPublished - 2003 2 11

ASJC Scopus subject areas

  • Clinical Neurology

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