Spontaneous regression of blastic plasmacytoid dendritic cell neoplasm following sepsis by Serratia marcescens: A case report and literature review

Akane Suzuki, Shori Abe, Kaori Koyama, Shinju Suzuki, Munenori Nagao, Masahiro Kobayashi, Jun Nomura, Tomomi Tsutsumi, Tomoki Takeda, Yumiko Oka, Yuko Shirota, Naruhiko Takasawa, Takao Kodera, Yoko Okitsu, Shinichiro Takahashi, Ryo Ichinohasama, Junichi Kameoka

研究成果: Article査読

抄録

Spontaneous regression is rare in patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN). An 85-year-old man presented with pancytopenia and skin lesions, and the bone marrow exhibited 79.6% CD4+, CD56+, CD123+, and TCL-1+ abnormal cells, with a normal karyotype; he was thus diagnosed with BPDCN. While being followed without chemotherapy, he was admitted due to sepsis induced by Serratia marcescens, which was successfully treated with antibiotics. Notably, his blood cell counts improved, and the skin lesions disappeared. To our knowledge, this is the first reported case of spontaneous regression of BPDCN with a decrease in tumor cells in the bone marrow following sepsis.

本文言語English
ページ(範囲)927-933
ページ数7
ジャーナルInternal Medicine
60
6
DOI
出版ステータスPublished - 2021

ASJC Scopus subject areas

  • 内科学

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